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Clinical Reproductive Medicine, by Bryan D. Cowan, David B. Seifer

Clinical Reproductive Medicine

by Bryan D. Cowan (Editor), David B. Seifer (Editor)

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Format: Hardcover, 1st ed., 292pp. 
ISBN: 0397511868
Publisher: Lippincott-Raven Publishers 
Pub. Date: November 1996

Description from

Book Description 

This volume offers authoritative, up-to-date guidance on the evaluation and treatment of reproductive endocrinopathies and infertility. The book reviews the underlying physiology and pathophysiology of these disorders, describes contemporary pharmacological and surgical treatments, and presents definitive treatment recommendations based on the latest scientific and clinical data.The first section focuses on reproductive endocrinopathies, such as disorders of puberty, irregularities of the ovarian-menstrual cycle, dysfunctional uterine bleeding, amenorrhea, hyperprolactinemia, and androgen excess disorders. Also included are chapters on menopause, oral contraceptives, and dynamic testing of glandular reserve. The second section discusses current methods for evaluation and treatment of infertility. Coverage includes detailed information on reproductive surgery, gamete technologies, gonadotropin-releasing hormone analogues, drugs used for ovulation induction, and molecular technologies in reproductive medicine, as well as on the correction of endometriosis, uterine anomalies, and ectopic pregnancy.

Book Info 

University of Mississippi, Jackson. Clinical text for obstetrician-gynecologists, general practitioners, internists, and students. Covers physiology, pathophysiology of reproductive endocrinopathies, and infertility treatments. 20 U.S. contributors. DNLM: Reproduction physiology.

Description from

From the Publisher 

Cowan, Bryan D., MD (Univ of Mississippi); Seifer, David B., MD(Ohio State Univ)

The contributors represent the specialties of obstetrics/gynecology and reproductive endocrinology. Most are from universities and medical centers in the U.S., including Bay State Medical Center, Univ of Mississippi, and Ohio State Univ.

From the Critics 

From Doody Review Services 
Reviewer: Elisa A. Hofmann, MD (University of Chicago Medical Center) 

Description: This book presents current clinical applications of reproductive medicine. The first section describes reproductive physiology and pathophysiology, and the second section focuses on various infertility treatments. 

Purpose: The authors hope this book will enable physicians to provide genuine and meaningful counseling, care, and diligence to infertile couples and women with reproductive endocrinopathies. 

Audience: The authors wrote this book primarily for primary care providers, general practitioners, and internists and secondarily for general obstetricians/gynecologists. The authors are credible authorities because they are all gynecologists, and the vast majority practice reproductive medicine. 

Features: The book is appropriately illustrated with numerous tables, figures, and algorithms depicting the evaluation and treatment of various reproductive endocrinopathies and causes of infertility. Most of the chapters contain current references. The chapter on androgen excess disorders, however, is lacking information and references pertaining to hyperinsulinemia as a factor in the etiology of polycystic ovary syndrome (PCOS) as well as some of the recently proposed treatment options for PCOS (metformin and troglitazone). One unique feature is that each chapter begins with a figure representing its primary subject matter as well as a list of the subject headings. These features focus the reader's attention by previewing the chapter's contents. 

Assessment: As an endocrine fellow, I have managed some of the endocrinopathiesdescribed in this text, and I found the book to be an accurate, useful, and reputable source of information. I also found the second section very educational because, as internists, we do not routinely manage infertility in our clinic. I would strongly recommend it to other internists as well as to general practitioners and general obstetricians/gynecologists, because patients with signs and symptoms of the endocrinopathies described can present to any of these physicians.

Table of Contents



1 Neuroregulation of the HPO Axis   3

2 Steroid Biosynthesis   11

3 Reproductive Peptide Hormones   21

4 Ovarian Phylogeny   29

5 Normal and Abnormal Sexual Development   37

6 Disorders of Puberty   49

7 Regulation of the Ovarian-Menstrual Cycle   61

8 Dysfunctional Uterine Bleeding   69

9 Amenorrhea   75

10 Hyperprolactinemia   85

11 Androgen Excess Disorders   95

12 Menopause   103

13 Dynamic Testing of Glandular Reserve   115

14 Oral Contraceptives   131

15 Gametogenesis   143

16 Implantation Biology   159

17 Infertility Evaluation   167

18 Endometriosis   175

19 Mullerian Anomalies   181

20 Ectopic Pregnancy   191

21 Reproductive Surgery   201

22 Gamete Technologies   213

23 Gonadotropin-Releasing Hormone Analogs   225

24 Ovulation Induction: Clomiphene Citrate and Menotropins   231

25 Recurrent Pregnancy Loss   239

26 Reproductive Immunology   247

27 Molecular Technologies in Reproductive Medicine   267

Appendix   281

Index   283

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